Rotary motion of DNA rotors on nanopores. Major row: raw video with the Cy5 channel of every rotor. Center row: corresponding solitary-particle localization outcomes of the two ends of the DNA rotors. The posture of the current body is marked as orange and blue dots, along with the trajectory of the 10 frames before The present body is proven as solid traces.
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Round the identical time, the team of Paul McEuen, who was then dependent on the University of California, Berkeley, confirmed equivalent results on ropes of bundled nanotubes. Depending on the wrapping angle, nanotubes can can be found in metallic or semiconducting variants, a prediction that we and Charles Lieber’s group at Harvard College independently confirmed applying scanning tunnelling spectroscopy experiments.
Sculpting nano-electrodes with a transmission electron beam for electrical and geometrical characterization of nanoparticles.
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Our investigate ranges through the biophysics of DNA to synthetic cells and past. Make sure you have a look beneath on the spectrum of our existing tasks.
‘At the outset we checked out biological devices with a physical look at and acted on The premise of the resources ceesdekker.net we understood. It took a number of years before we started out Performing more on the big biological concerns. I then began to simply call it nanobiology, a time period that didn't exist at the time.
2011, initially in vitro measurements of transportation across a single biomimetic nuclear pore complex; development of multiplexed magnetic tweezers for kilo-molecule experiments; and fixed the system of homology recognition in DNA homologous recombination
2003, demonstrated the very first biosensors produced out of a carbon nanotube; fixed the framework and mechanism of DNA fix proteins; and discovery of a brand new technique for fabricating good-point out nanopores for DNA translocation
1). The existing–voltage curves showed major modulations with gate voltage, even at room temperature, which was in keeping with band bending inside a ~0.six eV bandgap semiconducting nanotube. These data also showed which the conductance might be modulated by 6 orders of magnitude by changing the gate voltage. The outcome of the function — a home-temperature transistor created from one carbon nanotube molecule — were revealed in Mother nature in Might 1998.
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Nature Physics many thanks the anonymous reviewers for his or her contribution for the peer review of the perform.
By way of example, we look at the nucleopore elaborate, a gateway involving the cell nucleus and the cytoplasm. This is a really challenging program and therefore challenging to examine in a mobile, so we use biomimetics. We reconstruct holes after which insert individual things in the nucleopore complex to review transport by it at the single-molecule stage.’
Dekker heeft fundamentele ontdekkingen gedaan op het gebied van koolstof nanobuisjes. Mede vanwege deze werkzaamheden is hij al jaren de meest geciteerde fysicus in Nederland. Tegenwoordig onderzoekt hij achieved enkel-molecuultechnieken de biofysica van moleculen in de biologische cel. Dekker is naast zijn wetenschappelijk werk ook bekend vanwege zijn belangstelling voor de relatie tussen geloof en wetenschap en de discussie rond intelligent layout in 2005. (nl)